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Determination of related substances in Ambroxol Hydrochloride Injection by HPLC
Pages: 226-228
Year: Issue:  3
Journal: World Phytomedicines

Abstract: 目的 采用HPLC法测定盐酸氨溴索注射液中的有关物质.方法 采用Agela Venusil MP C18柱(250 mm×4.6mm,5 μm),以磷酸氢二铵缓冲液(pH 4.0) -甲醇(40∶60)为流动相,体积流量为1.0 mL/min,检测波长为250 nm,柱温:30℃.结果盐酸氨溴索和反式-4-[6,8-二溴-1,4-二氢喹唑啉-3(2H)]环己醇的最小检出限分别为15、30 ng;杂...
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