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Journal Articles
Effects of Ketamine and Alcohol on Learning and Memory Impairment in Mice
Pages: 115-119
Year: Issue:  2
Journal: Journal of Forensic Medicine

Keyword:  法医毒理学氯胺酮酒精学习记忆小鼠;
Abstract: 目的 研究氯胺酮与酒精对小鼠学习记忆的行为学及相关神经递质的影响.方法 40只小鼠分为4组:对照组、氯胺酮组、酒精组、氯胺酮酒精联合给药组,每组10只.氯胺酮和酒精分别采用腹腔注射和灌胃给药的方式,1次/d,连续14d.通过跳台和水迷宫实验检测各组小鼠的学习记忆能力,通过测定小鼠大脑组织中乙酰胆碱(acetylcholine,ACh)和5-羟色胺(5-hydroxy tryptamine,5-HT...
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