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Role and mechanism of prostacyclin in splanchnic hyperdynamic circulation in portal hypertension
Author(s): 
Pages: 257-261
Year: Issue:  3
Journal: Journal of Surgery Concepts & Practice

Keyword:  门静脉高压症高动力循环前列环素环氧合酶;
Abstract: 目的:研究前列环素(PGI2)在门静脉高压症(PHT)内脏高动力循环形成中的作用及机制.方法:观察四氯化碳致肝硬化门静脉高压症组(PHT组,n=8)和对照组(N组,n=8)大鼠的门静脉压力(PP)、离体肠系膜微动脉对去甲肾上腺素(NE)的反应性、肠系膜动脉内环氧合酶(COX)表达和下腔静脉血浆6-酮-前列腺素F1α (6-keto-PGF1α)浓度,以及吲哚美辛(INDO)对PHT组大鼠的影响.结...
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