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Determination of Diphenhydramine in Anti-Acne Cosmetics by HPLC
Author(s): 
Pages: 1046-1049
Year: Issue:  2
Journal: Chinese Journal of Spectroscopy Laboratory

Keyword:  高效液相色谱法苯海拉明祛痘化妆品;
Abstract: 建立了高效液相色谱法测定祛痘类化妆品中禁用组分苯海拉明的含量.采用Inertsil CN-3色谱柱,流动相为乙腈-水-三乙胺(50 ∶ 50 ∶ 0.5,用冰醋酸调节pH至6.5),检测波长258nm,流速1.0mL/min,柱温25℃.苯海拉明在0.05-2.00mg/mL内呈良好线性(r=1.0000),平均回收率103.2%(RSD=0.70%,n=6);方法检出限(S/N=3)为50μg/...
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