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Effects of somatostatin analogues octreotide on peptic ulcer complicated with upper gastrointestinal bleeding in elderly patients
Author(s): ZOU Ke-wen
Pages: 641-
642,645
Year: 2012
Issue:
5
Journal: Journal of Hainan Medical College
Keyword: 奥曲肽; 老年患者; 消化性溃疡; 上消化道大出血;
Abstract: 目的:观察奥曲肽对老年患者消化性溃疡并上消化道大出血的治疗效果。方法:选取符合诊断标准的消化性溃疡合并上消化道出血老年患者70例,随机分成观察组和对照组,每组各35例,两组患者均给予抑酸、止血、补液对症支持治疗,观察组在此治疗基础上加用奥曲肽,观察两组治疗效果、总有效率以及1周内再出血情况。结果:奥曲肽治疗组总有效率97.14%,常规治疗组总有效率88.57%,两组比较差异具有统计学意义(P<0.05)。奥曲肽组1周内再出血率0.00%,常规治疗组1周内再出血率11.43%,两组比较差异具有统计学意义(P<0.05)。结论:奥曲肽治疗老年患者消化道溃疡合并上消化道出血疗效显著,能降低再出血率,减少急诊手术以及消化道大出血死亡率,值得临床推广。
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