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A clinicopathologic and immunohistochemical study of gastric stromal tumors
Author(s): 
Pages: 579-581
Year: Issue:  6
Journal: CHINESE JOURNAL OF CANCER

Keyword:  胃间质瘤临床病理免疫组化;
Abstract: 目的:探讨胃间质瘤(gastricstromaltumor,GST)的组织发生、组织分型及预后关系.方法:结合临床病理特点与免疫组化CD34、S-100蛋白、SMA标记对60例GST进行观察.结果:GST良、恶性与肿瘤大小、核分裂像多少、细胞异型性、细胞密度、肿瘤组织浸润相关(P<0.05),而与肿瘤出血、坏死无关(P>0.05);CD34、S-100蛋白、SMA阳性率与肿瘤分化程度、转移生存率相关(P<0.05).S-100蛋白、SMA阳性率越低,肿瘤恶性程度越高,越易发生转移,生存率越低,CD34则相反.结论:CD34、SMA和S-100蛋白表达可为GST预后提供有价值参考.
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