A Comparison of Effects of Seven Intravenous Anesthetics on Hemodynamics in Humans
Author(s): WU Xinwen, ZHUANG Yongjing, CHEN Yongwei, WANG Zhongzuo
Pages: 283-287
Year: 2000 Issue: 6
Journal: THE JOURNAL OF CLINICAL ANESTHESIOLOGY
Keyword: 静脉麻醉药; 血流动力学;
Abstract: 目的:比较常用静脉麻醉药对血流动力学的影响.方法:80例拟行全麻患者随机分成八组,分别给予生理盐水10ml、硫喷妥钠6mg/kg、异丙酚2.5mg/kg、咪唑安定0.3mg/kg、依托咪酯丙二醇制剂0.3mg/kg、依托咪酯乳剂0.3mg/kg、氯胺酮2mg/kg和芬太尼5μg/kg.用Ultima监测仪和阻抗法记录并计算血液动力学有关参数.结果:就BP而言,其降幅排序为异丙酚＞咪唑安定＞硫喷妥钠＞依托咪酯,芬太尼组无明显变化,氯胺酮组明显升高.对SI和CI的抑制,咪唑安定＞硫喷妥钠＞异丙酚＞依托咪酯＞芬太尼＞氯胺酮.左室作功除氯胺酮组明显增加外,其他组均降低,其排序为咪唑安定＞硫喷妥钠＞异丙酚＞依托咪酯＞芬太尼.结论:芬太尼、依托咪酯对血液动力学影响较小,硫喷妥钠、异丙酚、咪唑安定影响较大,氯胺酮可有不同程度的心血管刺激作用.
Pages: 283-287
Year: 2000 Issue: 6
Journal: THE JOURNAL OF CLINICAL ANESTHESIOLOGY
Keyword: 静脉麻醉药; 血流动力学;
Abstract: 目的:比较常用静脉麻醉药对血流动力学的影响.方法:80例拟行全麻患者随机分成八组,分别给予生理盐水10ml、硫喷妥钠6mg/kg、异丙酚2.5mg/kg、咪唑安定0.3mg/kg、依托咪酯丙二醇制剂0.3mg/kg、依托咪酯乳剂0.3mg/kg、氯胺酮2mg/kg和芬太尼5μg/kg.用Ultima监测仪和阻抗法记录并计算血液动力学有关参数.结果:就BP而言,其降幅排序为异丙酚＞咪唑安定＞硫喷妥钠＞依托咪酯,芬太尼组无明显变化,氯胺酮组明显升高.对SI和CI的抑制,咪唑安定＞硫喷妥钠＞异丙酚＞依托咪酯＞芬太尼＞氯胺酮.左室作功除氯胺酮组明显增加外,其他组均降低,其排序为咪唑安定＞硫喷妥钠＞异丙酚＞依托咪酯＞芬太尼.结论:芬太尼、依托咪酯对血液动力学影响较小,硫喷妥钠、异丙酚、咪唑安定影响较大,氯胺酮可有不同程度的心血管刺激作用.
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