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Window Effect of Tumor Cell Apoptosis Induced by Nanopulses
Author(s): 
Pages: 2797-2802
Year: Issue:  11
Journal: High Voltage Engineering

Keyword:  ns级脉冲电场肿瘤细胞凋亡率SKOV3细胞窗口效应凋亡率与坏死率差值;
Abstract: ns级脉冲电场诱导肿瘤细胞凋亡用于肿瘤病变的治疗,展现出令人振奋的临床应用前景.由于ns级脉冲电场诱导的凋亡率高低与场强一脉宽等参数存在一定的选择性,使得目前脉冲参数的选择存在较大的盲目性.为寻求诱导肿瘤细胞有效凋亡的ns级脉冲电场参数,将不同参数组合(电压幅值9 kV,脉宽分别为1、50、100与200 ns,脉冲个数分别为10、30、60与80,频率1 Hz)的ns级脉冲电场作用于SKOV3细...
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