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Effect of simvastatin on the function of platelet damaged by advanced glycation end products
Author(s): LI Wei, LIU Yuan, YU Lin-qi
Pages: 697-
700
Year: 2011
Issue:
9
Journal: Acta Academiae Medicinae CPAF
Keyword: 辛伐他汀; 糖基化终产物; 血小板; 一氧化氮;
Abstract: [目的]探讨辛伐他汀抑制糖基化终产物损伤血小板功能的机制.[方法]首先提取正常人血小板作为研究对象并随机分为4组进行对比研究:对照组、辛伐他汀(50 μmol/L)组、糖基化终产物(advanced glycation ends products,AGEs)(200 mg/L)组以及辛伐他汀(50 μmol/L)和AGEs(200 mg/L)共同作用组.在实验中分别检测3个重要指标,包括血小板功能...
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