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Advancements of miR-21 and Gynecologic Neoplasms
Author(s): YA N Li-li
Pages: 537-
540
Year: 2011
Issue:
6
Journal: Journal of International Obstetrics and Gynecology
Abstract: 微小RNA (miRNA)是一类分布十分广泛的内源性非编码RNA,在动物、植物和病毒中广泛存在.miRNA与肿瘤的发生、发展和预后有关,并在肿瘤的增殖、分化及凋亡等方面有重要的作用.大量研究结果表明,许多miRNA可作为原癌基因或抑癌基因,在肿瘤的发生和发展中发挥重要作用,其中miR-21最受重视.miR-21作为较早发现的人类miRNA之一,因其较为明确的存在背景,而成为人类miRNA功能研究中...
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