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Efficacy of low-dose interferon therapy for treating chronic hepatitis C patients who cannot tolerate standard treatment
Author(s): CAO Zhen-huan, LIU Ya-li, ZHENG Yan-hong, JI Shu-dan, WANG Jun-li, LIAO Jian-hua, ZHANG Cun-yuan, CHEN Xin-yue
Pages: 20-
24
Year: 2012
Issue:
1
Journal: Chinese Journal of Hepatology
Keyword: Hepatitis C; chronic; Interferon; low dose; Virology responses;
Abstract: 目的 针对不能耐受标准治疗方案的慢性丙型肝炎(CHC)患者,探索低剂量干扰素联合利巴韦林长期维持治疗的效果,并分析与疗效相关的可能影响因素. 方法 对于白细胞低下、甲状腺功能异常等多种原因不能耐受标准治疗方案的CHC患者46例,给予个体化低剂量干扰素(标准干扰素60万~300万IU隔日一次,聚乙二醇干扰素50 ~ 90μg/周)联合利巴韦林0.6 ~ 0.9 g/d 长期维持治疗,疗程≥72周...
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