Author(s): GAO Zhenqin, HU Yongbin, PENG Jingwu, DENG Zhenghao, LIANG Guannan, JIANG Haiying, ZHOU Jianhua
Pages: 1085-1089
Year: 2011 Issue:  11
Journal: Journal of Central South University(Medical Sciences)
Keyword:  二氧化硅; 细胞外信号调节激酶; 人支气管上皮细胞; 上皮-间质转型;
Abstract: 目的:探讨细胞外信号调节激酶(extracellular signal-regulated kinase,ERK)信号通路在二氧化硅( SiO2)诱导人支气管上皮细胞(human bronchial epithelial cells,HBEC)上皮-间质转型(epithelial-mesenchymal transition,EMT)中的作用机制.方法:SiO2(0～ 300 μg/mL)处理HB...