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The effect of learning and memory on c-fos gene expression in brain
Author(s): 
Pages: 228-230,216
Year: Issue:  5
Journal: CHINESE BULLETIN OF LIFE SCIENCES

Keyword:  c-fos基因学习记忆训练;
Abstract: 学习记忆是人和动物重要的脑功能,大量事实表明,学习记忆过程与脑内c-fos基因的表达密切相关.由学习记忆所诱导的c-fos基因表达在脑内广泛分布,以皮层、海马和边缘系统为多,依学习记忆训练模型的不同,其表达时程有所差异,但一般于训练后立即或30分钟左右出现,1~2小时左右达峰值.被动和主动回避训练、光辨别训练及味觉厌恶性条件反射训练等多种学习记忆模型均可诱导脑内c-fos基因的表达.其他影响学习记忆过程的因素,如长时程增强和某些药物也都在一定程度上影响c-fos基因的表达.
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