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Homer Protein Expression after Focal Brain Contusion in Rats
Author(s): WANG Fu-yuan, LI Ru-bo, LIANG Hong-xia, SHEN Yu, GUO Xiao-chong, WANG Zheng-yin
Pages: 409-
412
Year: 2011
Issue:
6
Journal: Journal of Forensic Medicine
Keyword: 法医病理学; 脑损伤; 印迹法; 蛋白质; 免疫组织化学; Homer蛋白; 大鼠;
Abstract: 目的 观察局灶性脑挫伤后Homer蛋白表达的变化规律,探讨其表达变化与损伤时间的相关性.方法 建立大鼠钝力性局灶性脑挫伤模型,应用免疫组织化学技术和Western印迹法观察脑损伤后不同时间脑组织中Homer蛋白表达的变化.结果 对照组、假手术组及伤后0.5h组脑组织中有少量Homer蛋白染色阳性细胞,伤后3h组脑组织Homer蛋白染色阳性细胞增多,伤后12h组阳性细胞数达到高峰,伤后1d起阳性细胞...
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