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Effects of valsartan and U0126 on atrial fibrosis and connexin40 remodeling in rats
Author(s): 
Pages: 1129-1134
Year: Issue:  12
Journal: Chinese Journal of Cardiology

Keyword:  ValsartanHeart atriaFibrosisConnexins;
Abstract: 目的 探讨缬沙坦与U0126对血管紧张素Ⅱ(angiotensin Ⅱ,Ang Ⅱ)诱导的大鼠心房纤维化和缝隙连接蛋白40( connexin 40,Cx40)重构的影响.方法 将32只雄性SD大鼠随机分为空白对照组(A组)、盐酸异丙基肾上腺素( isopreterenol,ISO)+二甲基亚砜(DMSO)组(B组)、ISO+U0126组(C组,U0126溶于DMSO中)、ISO+缬沙坦+DMSO...
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