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Analysis of HBV mutation resistant to adefovir dipivoxil
Author(s): 
Pages: 477-478,485
Year: Issue:  5
Journal: Experimental and Laboratory Medicine

Abstract: 目的 了解接受阿德福韦治疗后HBV的基因变异情况.方法 收集我院2007年1月至2009年1月门诊接受阿德福韦治疗的慢性乙肝患者100例,对其进行为期2年的随访,于治疗的不同阶段采用巢式聚合酶链反应一限制性片段长度多态(ntPCR-RFLP)技术对HBV病毒基因变异(rtN236T变异和rtA181V变异)进行检测,了解HBV基因突变情况.结果 6个月检测无变异基因;12个月检测出变异基因病例3例...
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