Simultaneous GC determination of methamphetamine and its metabolite amphetamine in hair
Author(s): JIANG Yan, SHEN Min, ZHAO Ziqin, SHEN Baohua, BO Jun, YE Yonghong
Pages: 222-224,227
Year: 2000 Issue: 4
Journal: JOURNAL OF FORENSIC MEDICINE
Keyword: 甲基苯丙胺; 苯丙胺; 毛发分析; GC/NPD; GC/MS;
Abstract: 介绍了毛发中甲基苯丙胺(MAMP)及代谢产物苯丙胺(AMP)的GC/NPD、GC/MS的定性定量分析方法.毛发用0.1mol/LHCl水解,4-苯基丁胺(4-PBA)为内标,液-液提取,三氟乙酸酐(TFA)衍生化.毛发用量为10mg,检出限为GC/NPD0.5ng/mg,GC/MS0.1ng/mg,回收率大于78%.该方法成功应用于染毒豚鼠毛发中MAMP及其代谢产物AMP浓度变化过程的测定.
Pages: 222-224,227
Year: 2000 Issue: 4
Journal: JOURNAL OF FORENSIC MEDICINE
Keyword: 甲基苯丙胺; 苯丙胺; 毛发分析; GC/NPD; GC/MS;
Abstract: 介绍了毛发中甲基苯丙胺(MAMP)及代谢产物苯丙胺(AMP)的GC/NPD、GC/MS的定性定量分析方法.毛发用0.1mol/LHCl水解,4-苯基丁胺(4-PBA)为内标,液-液提取,三氟乙酸酐(TFA)衍生化.毛发用量为10mg,检出限为GC/NPD0.5ng/mg,GC/MS0.1ng/mg,回收率大于78%.该方法成功应用于染毒豚鼠毛发中MAMP及其代谢产物AMP浓度变化过程的测定.
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