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wei suo xing wei yan da shu p16,bcl-2,pcna de biao da ji ye suan de yu fang zuo yong
Author(s): 
Pages: 3324-3327
Year: Issue:  17
Journal: Chinese Journal of Gerontology

Keyword:  萎缩性胃炎胃黏膜叶酸细胞增殖;
Abstract: 目的 研究萎缩性胃炎大鼠胃黏膜中FCNA,p16,bcl-2蛋白表达情况,探讨这些调控因子改变及叶酸预防性治疗对萎缩性胃炎形成及增殖调控的影响.方法 大鼠随机分为对照组,模型组及叶酸预防组,制作萎缩性胃炎模型,叶酸预防组造模同时予叶酸溶液灌胃,共6个月.血清及组织叶酸采用化学发光法检测,胃黏膜组织分别行常规HE染色及免疫组织化学染色,免疫组化结果通过图像分析检测蛋白表达阳性面积及密度.结果 模型组...
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