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Proliferating cell nuclear antigen and c-Fos protein regulating development of the human embryonic spinal cord
Pages: 836-839
Year: Issue:  6
Journal: Acta Anatomica Sinica

Abstract: 目的 探讨人胚胎发育早、中期脊髓内神经细胞增殖与凋亡的变化规律及其相关蛋白增殖性细胞核抗原(PCNA)和c-Fos在脊髓中的分布规律及其表达意义.方法 应用免疫组织化学法检测第2~4月龄段人胚胎(共16例)脊髓组织中央管、前角和后角处PCNA和c-Fos蛋白的表达情况.结果 第2个月龄段,人胚脊髓基板处无PCNA蛋白阳性表达,中央管神经上皮细胞和翼板均有PCNA蛋白阳性表达;而c-Fos蛋白在脊髓...
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