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Effect of melatonin on proliferation inhibition and apoptosis induction in the murine foregastric carcinoma cell in vivo and in vitro
Pages: 792-797
Year: Issue:  6
Journal: Acta Anatomica Sinica

Abstract: 目的 探讨褪黑素(MLT)在体内外对小鼠前胃癌(MFC)细胞的增殖抑制与凋亡诱导作用.方法 体内实验:建立荷胃癌小鼠模型,随机分为5组:A.正常对照组;B.荷瘤空白对照组:每日注射生理盐水100 mg/kg;C.小剂量褪黑素组:荷瘤成功后(接种第6天起)每日腹腔注射MLT 25 mg/kg;D.中剂量MLT组:每日腹腔注射MLT 50 mg/kg;E.大剂量MLT组:每日腹腔注射MLT 100 m...
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