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Effects of diammonium glycyrrhizinate lipid ligand on NF-κB expression in the rat with nonalcoholic fatty liver disease
Author(s): 
Pages: 815-819
Year: Issue:  6
Journal: Acta Anatomica Sinica

Keyword:  p65免疫印迹法大鼠;
Abstract: 目的 探讨甘草酸二铵脂质配位体(DGLL)对非酒精性脂肪肝(NAFLD)大鼠的治疗作用及其相关机制.方法 60只SD大鼠随机分为6组:正常对照组、模型组、DGLL(30、60、120mg/kg)组及阳性对照药联苯双酯(200mg/kg)组,每组10只.采用高脂乳剂灌胃建立大鼠NAFLD模型,并给予DGLL干预,9周后观察大鼠血脂、脂质过氧化水平改变;肝脏免疫组织化学观察NF-κB p65病理变化...
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