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Effect of diabetes on the differentiation and osteogenesis mineralization of femoral head growth plate in rats
Author(s): 
Pages: 825-831
Year: Issue:  6
Journal: Acta Anatomica Sinica

Keyword:  糖尿病生长板胶原纤维蛋白聚糖血管内皮生长因子墨汁灌注原位杂交大鼠;
Abstract: 目的 探讨糖尿病对长骨发育的影响机制.方法 建立速发型链脲佐菌素(STZ)糖尿病大鼠模型,分为糖尿病5周组(DM1)、10周组(DM2)及15周组(DM3),每组10只,另设正常5周组(CON1)、10周组(CON2)及15周组(CON3),每组10只,共60只.对各组大鼠股骨头生长板,光镜下作组织病理学分析及组织计量学测定;利用Van Gieson胶原纤维染色法观察胶原纤维沉积变化;墨汁灌注行边...
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