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Effect of transplanted bone marrow mesenchymal stem cells on the repair of colon tissues of rats with ulcerative colitis
Author(s): 
Pages: 820-824
Year: Issue:  6
Journal: Acta Anatomica Sinica

Keyword:  间充质干细胞溃疡性结肠炎移植修复免疫荧光大鼠;
Abstract: 目的 探讨大鼠骨髓间充质干细胞(MSCs)移植后对溃疡性结肠炎(UC)大鼠结肠的修复作用.方法 分离培养、荧光标记大鼠MSCs.SD大鼠45只随机分为3组,A、B组用免疫复合法诱导UC模型,C组为正常对照组.A组移植MSCs,B组移植等量PBS.移植后3d、7d、14d取结肠组织制作石蜡切片,观察病理变化;另取A组结肠组织制作冷冻切片,荧光显微镜下观察移植细胞的分布,免疫荧光染色后激光共焦显微镜下...
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