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NF-κB p65 siRNA Mediated Cell Apoptosis of Tongue Squamous Cell Carcinoma Tca8113 Cells and its Related Molecular Mechanism
Author(s): 
Pages: 744-748
Year: Issue:  9
Journal: Journal of Oral Science Research

Keyword:  核因子一κB信号途径舌鳞状细胞癌小干扰RNA细胞凋亡;
Abstract: 目的:研究下调核因子κB (nuclearfactor-kappa B,NF-κB)/p65基因的表达对舌鳞状细胞癌Tca8113细胞凋亡的影响,并探讨Tca8113细胞凋亡可能的分子机制.方法:利用脂质体2000将终浓度为100 nmol/L的p65 siRNA转染舌鳞状细胞癌Tca8113细胞,通过RT- PCR检测0、24、48和72 h p65 mRNA的表达,并通过流式细胞术检测转染前后...
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