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Alteration of interstitial cells of Cajal in the colon of slow transit constipation rats
Pages: 3290-3292
Year: Issue:  18
Journal: The Journal of Practical Medicine

Abstract: 目的:研究慢传榆型便秘(STC)大鼠结肠内cajal间质细胞(ICC)的变化,探讨ICC在STC发病机制中的作用.方法:用复方苯乙哌啶灌胃法建立STC大鼠模型,免疫组化法检测大鼠结肠ICC,分析大鼠结肠不同部位ICC的变化.结果:STC组大鼠结肠ICC比对照组明显减少.结论:STC大鼠结肠内ICC明显减少,提示ICC在STC的发病机制中可能起重要作用.
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