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The relationship of polymorphism of methionine synthase gene and plasma homocysteine level with intracranial aneurysm
Author(s): 
Pages: 3522-3525
Year: Issue:  19
Journal: The Journal of Practical Medicine

Keyword:  动脉瘤同型半胱氨酸蛋氨酸合成酶还原酶基因多态性;
Abstract: 目的:探讨同型半胱氨酸(Hcy)及其代谢关键酶蛋氨酸合成酶还原酶(methionine synthase reductase,MTRR)基因多态性与颅内动脉瘤的关系.方法:采用化学发光技术检测76例颅内动脉瘤患者(颅内动脉瘤组)和77例健康成人(对照组)的血浆Hcy水平,并利用聚合酶链反应-限制性内切酶片段长度多态性技术(PCR-RFLP)检测其代谢关键酶MTRR基因多态性.结果:颅内动脉瘤患者血...
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