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Effects of propofol on the activation of ASK1 in HEK293 cells
Author(s): 
Pages: 505-508,封3
Year: Issue:  5
Journal: Journal of Tropical Medicine

Abstract: 目的 探讨在H2O2刺激下,异丙酚对细胞中Daxx-ASK1信号通路的影响.方法 对体外培养的HEK293细胞分为对照组、H2O2刺激组以及H2O2刺激合并异丙酚处理组.采用免疫荧光、Western blot及MTT等方法,观察异丙酚预处理对H2O2刺激下的HEK293细胞存活率以及细胞中Fas死亡结构域相关蛋白(Daxx)的亚细胞定位以及凋亡信号调节激酶1(ASK1)激活的影响.结果 在200~...
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