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Issue:
Pharmacogenomics-related P450 and ABCB1 Polymorphisms and SNP Detection Technology
Author(s):
SUI Weiguo
,
ZHANG Ruohan
,
CHEN Jiejing
,
DAI Yong
Pages:
363
-
367
Year:
2011
Issue:
4
Journal:
Journal of Medical Molecular Biology
Abstract:
药物基因组学(phamacogenomics)是临床检测遗传差异引起药物应答个体性差异的学科,它涉及药物代谢和有害的药物反应的预测等方面的内容.个性化药物和个性化治疗发展的关键条件是能够快速简便的检测出病人的遗传多态性.文章综述了药物基因相关问题,细胞色素酶P450和ABCB1转运蛋白的遗传多态性以及检测遗传多态性的相关技术.
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