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Downregulation of HDPR1 enhances invasion of lung cancer cells
Author(s): 
Pages: 419-423
Year: Issue:  5
Journal: Progress of Anatomical Sciences

Abstract: 目的 研究HDPR1(human homologue of Dapper)在肺癌表达与p120ctn和β-catenin异常表达相关性的可能调节机制.方法 运用siRNA技术沉默肺癌细胞系的HDPR1表达后,应用RT-PCR和Westem blot技术观察p120ctn和β-caterun的表达情况,并应用基质胶侵袭实验观察肺癌细胞的侵袭能力.结果 沉默肺癌细胞系中HDPRI表达后,p120ctn...
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