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Expression of TLR7 and TLR9 mRNA in the peripheral blood mononuclear cells of patients with systemic lupus erythematosus
Author(s): 
Pages: 542-545
Year: Issue:  8
Journal: China journal of Leprosy and Skin Diseases

Keyword:  红斑狼疮系统性Toll样受体7Toll样受体9单个核细胞;
Abstract: 目的:检测Toll样受体7(TLR7)mRNA及TLR9 mRNA在系统性红斑狼疮(SLE)患者外周血单个核细胞内的表达.方法:运用逆转录-聚合酶链式反应(RT-PCR)半定量方法检测40例SLE患者(活动期25例,稳定期15例)和30名健康对照者外周血单个核细胞TLR7和TLR9 mRNA表达水平.结果:活动期SLE患者外周血单个核细胞TLR7 mRNA表达显著高于稳定期患者和正常人(Ps<0....
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