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Study on the therapy of hepatic failure using hepatocyte-like cells derived from bone marrow transplantation
Author(s): 
Pages: 2398-2400,封2
Year: Issue:  24
Journal: Chongqing Medical Journal

Abstract: 目的 探讨骨髓源肝细胞样细胞移植对急性肝功能衰竭的治疗作用.方法 体外诱导大鼠骨髓间质干细胞(BMSCs)分化,以BST-1、清蛋白(ALB)为分子标志,采用逆转录聚合酶链反应(RT-PCR)和流式细胞技术(FCM)检测其分化状态.构建大鼠急性肝功能衰竭模型,随机分为两组:实验组(骨髓源肝细胞样细胞移植)和对照组,结合多项血生化指标、病理形态学和生存状况综合评估骨髓源肝细胞对肝功能重建的影响.结果...
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