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Clinical Analysis of Expression of Multidrug Resistance-associated Protein in Gastric Carcinoma
Author(s): 
Pages: 293-297
Year: Issue:  5
Journal: Chinese Journal of Gastroenterology

Abstract: 背景:胃癌对化疗药物原发或继发不敏感可致肿瘤多药耐药.目的:探讨胃癌组织中多药耐药相关蛋白P糖蛋白(P-gp)、谷胱甘肽S-转移酶(GST)-π、Bcl-xL的表达及其意义.方法:收集胃癌手术标本113例,每例标本选取肿瘤组织、距病灶5 cm以上的正常胃黏膜组织各1块.以免疫组化法检测多药耐药相关蛋白P-gp、GST-π、Bcl-xL的定位和表达,并与胃癌主要临床病理特征行相关性分析.结果:胃癌组...
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