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Association of MxA Gene Promoter Polymorphisms with the Clearance of Hepatitis B Virus Infection
Author(s): 
Pages: 17-20
Year: Issue:  3
Journal: Journal of Modern Laboratory Medicine

Abstract: 目的 探讨干扰素诱导的黏病毒抗性蛋白A(MxA)基因单核苷酸多态性(SNP)对乙型肝炎病毒(HBV)感染自然转归的影响.方法 收集湖北地区160例HBV自限感染者和243例慢性HBV感染者的外周血标本,应用聚合酶链反应-限制性片段长度多态性分析方法,检测MxA启动子-88,-123位点基因型.结果 MxA启动子-88G/T位点基因型和等位基因在慢性HBV感染者和自限性感染者中的分布差异有高度显著性...
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