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Systemic oxidative stress induced by intratracheal instilling with PM10 in rats
Author(s): 
Pages: 352-355
Year: Issue:  3
Journal: Journal of Peking University(Health Sciences)

Keyword:  空气污染颗粒物质氧化性应激大鼠;
Abstract: 目的:探讨大气可吸入颗粒物对大鼠的氧化应激作用.方法:将24只体重为320~360 g的雄性Wistar大鼠随机分为4组,即生理盐水对照组和颗粒物低、中、高剂量组(3.75、7.5、15 mg/kg).染毒采用一次性气管滴注颗粒物,24 h后处死动物,测定血液中的超氧化物歧化酶(superoxide dismutase,SOD)活性和丙二醛(malondialdehyde,MDA)含量,以及心肺组...
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