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The expression of laminin within cancer cells and the prognosis in human breast cancer
Author(s): 
Pages: 195-196
Year: Issue:  3
Journal: JOURNAL OF PRACTICAL ONCOLOGY

Keyword:  乳腺肿瘤/病理学预后层粘连蛋白免疫组织化学;
Abstract: 目的 探讨肿瘤细胞内层粘蛋白表达与乳腺癌预后的关系.方法 用免疫组化和微波抗原修复技术,检测78例原发乳腺癌细胞内层粘蛋白的表达.结果 本组乳腺癌患者的术后5年生存率为61.5%,术后平均生存时间59.6月.死亡组和生存组的层粘蛋白表达率分别为66.7%和54.2%.腋淋巴结状况、肿瘤大小、组织学分级和TNM分期均是影响乳腺癌预后的重要因素.层粘蛋白阴性表达组术后平均生存时间明显较阳性组长(P<0.05).结论 肿瘤细胞内层粘蛋白表达与乳腺癌的术后生存时间相关.
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