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Effect of zebularine on proliferation of human ovarian cancer cell line and its mechanism
Author(s): 
Pages: 545-549
Year: Issue:  4
Journal: Journal of Southeast University(Medical Science Edition)

Abstract: 目的:观察去甲基化制剂zebularine(Zeb)对体外培养的卵巢癌细胞A2780的生长抑制作用,并进一步探讨其作用机制.方法:应用不同浓度(50、100、200 μmol·L-1) 的Zeb处理体外培养的卵巢癌细胞A2780;应用MTT法检测细胞增殖活性,流式细胞仪检测细胞周期分布,Annexin V-FITC染色法检测细胞凋亡率.结果:100、200 μmol·L-1的Zeb处理卵巢癌细胞A...
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