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Relationship Between HCV Infection and Hepatocarcinoma
Author(s): LI Man, FENG De-yun
Pages: 1797-
1800
Year: 2011
Issue:
9
Journal: Biomagnetism
Keyword: 丙型肝炎病毒; 肝细胞肝癌; 发生机制;
Abstract: 世界上有数亿的人口患有丙型肝炎,而丙型肝炎病毒(HCV)的感染易转为慢性,引起肝细胞炎性坏死及再生,导致肝纤维化、硬化甚至肝细胞癌(HCC),是危害人类健康的一个重要卫生问题。HCV的感染可导致HCC的发生,但HCV相关性HCC的发生机制尚不清楚。免疫逃避机制是感染慢性化的一个重要原因,病毒通过其基因组编码的蛋白使肝细胞发生转化,可能是肝细胞癌变的重要机制。
Citations
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