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Effects of stretch in different frequencies on histologic appearance and expressions of typeⅠand type Ⅲ collagen protein in Achilles tendon of rabbits
Author(s): WU Zi-ying, CHEN Shi-yi, LI Yun-xia, CHEN Ji-wu, HUA Ying-hui
Pages: 113-
116
Year: 2011
Issue:
2
Journal: Journal of Fudan University(Medical Sciences)
Keyword: 跟腱; 牵拉频率; 组织学; Ⅰ型胶原; Ⅲ型胶原; 兔;
Abstract: 目的 观察不同频率牵拉对兔跟腱组织学表现和Ⅰ型、Ⅲ型胶原蛋白表达的影响,探讨牵拉频率与腱病之间的关系.方法 45只雄性新西兰大白兔随机分成3组,其中一组作为对照组未施加电刺激,另两组施加电刺激腓肠肌以牵拉跟腱,电刺激频率分别为0.17和1 Hz.光镜下观察兔跟腱组织学变化,免疫组化检测Ⅰ型、Ⅲ型胶原蛋白的表达情况.结果 牵拉4周后,1 Hz组Ⅰ型胶原明显减少,Ⅲ型胶原表达明显增加,但胶原总量减少....
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