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Application of Nucleic Acids and Proteins in Estimation of Postmortem Interval
Author(s): LI Wen-can, ZHANG Ping, CHEN Long
Pages: 50-
53
Year: 2011
Issue:
1
Journal: Journal of Forensic Medicine
Abstract: 死亡时间(postmortem interval,PMI)推断一直是法医学研究的重点与难点.机体死亡后,组织细胞发生自溶,核酸等大分子物质发生降解,其中DNA含量呈逐渐下降趋势,与PMI具有一定的线性关系,管家基因β-actin、GAPDH mRNA具有一定的稳定性,也可作为内参照进行PMI推测.本文综述了目前DNA、RNA以及蛋白质在PMI推断中的研究进展以及存在的问题,以期为法医学PMI的推断...
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