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The expression of 5-HTR2C in the hippocampal of the anger-in and anger-out animal model
Pages: 325-328
Year: Issue:  3
Journal: Chinese Pharmacological Bulletin

Keyword:  RT-PCRWestern blot5-HTR2C;
Abstract: 目的 怒是影响人类健康的重要情志因素,分为愤怒和郁怒两种表达方式,两者诱发病证的机制尚未完全明确.该文主要探索愤怒、郁怒情志反应的微观机制.方法 采用居住入侵和社会隔离的方法制备愤怒、郁怒反应大鼠模型,并分别予以调肝方药经前平颗粒、经前舒颗粒干预,以正常大鼠作为对照,分别取愤怒、郁怒模型组以及经前平、经前舒给药组大鼠的海马用以基因芯片检测,初步筛选出与愤怒、郁怒密切相关的基因5-HTR2C、GAB...
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