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on expression of vascular cell adhesion factor-1 in mouse macrophages
Pages: 443-444
Year: Issue:  3
Journal: Chinese Pharmacological Bulletin

Keyword:  血管细胞黏附因子-1儿茶素抗氧化巨噬细胞氧化低密度脂蛋白动脉粥样硬化;
Abstract:  血管细胞黏附因子介导的血管炎性病变是很多疾病[如动脉粥样硬化(atherosclerosis,AS)[1]、风湿病、肾病等]共同的病理基础.研究发现[2]AS的血管壁中有VCAM-1的大量表达.过量表达的VCAM-1介导的炎症反应参与了AS发生发展的全过程[3].儿茶素(catechin)是从茶叶中提取的酚类物质,有良好的调血脂抗AS作用.
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