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Effects of prostaglandin E1 on PKC and HSP70 in ischemia/reperfusion preconditioning Myocytes
Pages: 402-405
Year: Issue:  3
Journal: Chinese Pharmacological Bulletin

Keyword:  前列腺素E1心肌缺血/再灌注Western blot蛋白激酶C药理性预适应热休克蛋白70;
Abstract: 目的 探讨前列腺素E1(PGE1)预处理对大鼠缺血/再灌组心肌PKC及HSP70表达的影响.方法 40只大鼠随机分成5组:正常对照组(C组)、缺血/再灌注组(I/R组)和PGE1 14,42,126 μg·L-1预处理组.应用Langendorff装置制备大鼠心肌缺血/再灌注损伤(myocardial ischemia reperfusion injury,MIRI)模型,以HE染色制备病理切片观...
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