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Inhibitory effects of Jiawei Foshousan on angiogenesis of endometriosis in rats model and its mechanism
Pages: 350-354
Year: Issue:  3
Journal: Chinese Pharmacological Bulletin

Keyword:  加味佛手散子宫内膜异位症血管生成大鼠VEGFendostatin;
Abstract: 目的 探讨复方中药新药加味佛手散抑制子宫内膜异位症(EMS)血管生成作用及机制.方法 采用子宫内膜自体移植法建立大鼠EMS模型,免疫组化和Western blot方法检测异位内膜组织中微血管密度(MVD)、血管内皮生长因子(VEGF)和内皮抑素(endostatin)蛋白的表达,放射免疫分析法(RIA)分别检测大鼠血清和异位内膜组织中前列腺素E2(PGE2)的含量.结果 加味佛手散0.045、0....
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