The progress of study on podocytes associated antigen in membranous nephropathy
Author(s): KANG Hui-xia
Pages: 121-124
Year: 2011 Issue: 1
Journal: International Journal of Urology and Nephrology
Abstract: 膜性肾病(Membranous Nephropathy,MN)是以肾小球基底膜上皮细胞免疫复合物沉积伴基底膜弥漫增厚为特征的一组疾病,病因未阐明者称为特发性膜性肾病(IMN).IMN是构成中老年患者原发性肾病综合征的常见疾病.蛋白尿是其主要表现之一,引起蛋白尿的主要机制之一是足细胞损伤,而足细胞是一种终末分化细胞,一旦损伤丢失,很难再生.因此,探讨足细胞损伤的病因及机制是广大肾脏病学者研究的热点.
Pages: 121-124
Year: 2011 Issue: 1
Journal: International Journal of Urology and Nephrology
Abstract: 膜性肾病(Membranous Nephropathy,MN)是以肾小球基底膜上皮细胞免疫复合物沉积伴基底膜弥漫增厚为特征的一组疾病,病因未阐明者称为特发性膜性肾病(IMN).IMN是构成中老年患者原发性肾病综合征的常见疾病.蛋白尿是其主要表现之一,引起蛋白尿的主要机制之一是足细胞损伤,而足细胞是一种终末分化细胞,一旦损伤丢失,很难再生.因此,探讨足细胞损伤的病因及机制是广大肾脏病学者研究的热点.
Citations
- The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border Kerjaschki D.Farquhar MG
- Membranous glomerulopathy:the evolving story Ronco P.Debiec H
- Antenatal membranous glomerulonephritis due to anti-neutral endopeptidase antibodies Debiec H.Guigonis V.Mougenot B
- Role of truncating mutations in MME gene in fetomaternal alloimmunisation and antenatal glomerulopathies Debiec H.Nanta J.Coulet F
- Neonatal disease in neutral endopeptidase alloimmunization:lessons for immunological monitoring Nortier JL.Debiec H.Tournay Y
- Fetomaternal alloimmunization with antenatal glomerulopathies Debiec H.Ronco P
- M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy Beck LH Jr.Bonegio RG.Lambeau G
- Podocyte antigens and glomerular disease Ronco P.Debiec H
- Antigen identification in membranous nephropathy moves toward targeted monitoring and new therapy Ronco P.Debiec H
- The podocyte's response to injury:role in proteinuria and glomerulosclerosis Shankland SJ
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