Comparative study of aripiprazole and quetiapine on treatment of schizophrenia
Author(s): WU Meng
Pages: 47-48
Year: 2010 Issue: 11
Journal: China Clinical Practical Medicine
Keyword: Schizophrenia; Aripizole; Quetiapine;
Abstract: 目的 比较阿立哌唑与奎硫平治疗精神分裂症患者的疗效与不良反应.方法 将142例首发精神分裂症患者,随机分为阿立哌唑组及奎硫平组进行治疗,分别在治疗前及治疗2、4、8周末采用阳性与阴性症状量表(PANSS)评定临床疗效,用治疗中出现的症状量表(TESS)评定药物不良反应.结果 阿立哌唑的疗效与奎硫平相当,阿立哌唑的显效率81.69%奎硫平的显效率78.87%,组间比较差异无显著性(P＞0.05).阿...
Pages: 47-48
Year: 2010 Issue: 11
Journal: China Clinical Practical Medicine
Keyword: Schizophrenia; Aripizole; Quetiapine;
Abstract: 目的 比较阿立哌唑与奎硫平治疗精神分裂症患者的疗效与不良反应.方法 将142例首发精神分裂症患者,随机分为阿立哌唑组及奎硫平组进行治疗,分别在治疗前及治疗2、4、8周末采用阳性与阴性症状量表(PANSS)评定临床疗效,用治疗中出现的症状量表(TESS)评定药物不良反应.结果 阿立哌唑的疗效与奎硫平相当,阿立哌唑的显效率81.69%奎硫平的显效率78.87%,组间比较差异无显著性(P＞0.05).阿...
Citations
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- BurrisKD,MolskiTF,XuC,et al.Aripiprazole,a novelantipsychotic,is a high-affinity partial agonist at human dopamine D2 receptors.J PharmacolExp Ther,2002,302(1):381-389.
- Jordan S,Koprivica V,Chen R,et al.The antipsychotic aripiprazole is a potent,partialagonistat the human 5-HT1A receptor.Eur J Pharmaco,l 2002,441(3):137-140.
- 童建明,杨正春.几种新型抗精神病药介绍.临床精神医学杂志,2005,159(3):182.
- Small JG,Hirsch SR,Arvanitis LA,et al.Quetiapine in patients with schizophrenia.A high-and low-dose double-bind comparisonwith placebo.Seroquel study Group.Arch Gen Psychiatry,1997,54(3):549-557.
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