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Effect of WTRPQ Formula on Ultrostructure of Cholinergic Nerve Endings in Spleen Deficiency Mice
Author(s): TONG Guangdong, YUAN Jing, LIU Huiling, HU Wen, WU Huaqiang, LI Hongtao, ZHANG Jinghu, YI Zuo, YANG Zuo
Pages: 75-
77
Year: 2000
Issue:
2
Journal: CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE ON GASTRO-SPLEEN
Keyword: 温补培元方; 脾虚模型; 胆碱能纤维; 超微结构;
Abstract: 目的:研究温补培元方治疗脾虚证作用机制.方法:利用大黄制成的大鼠脾虚模型,并用从新安著名温补培元医家案中总结出的温补培元方进行治疗,在电镜下观察其小肠肌间神经丛胆碱能神经终末的清亮小泡的数量,运用立体定量分析法进行计算.结果:发现用药组ACh终末的清亮小泡数明显低于对照组(P<0.05).结论:提示该方有明显减少清亮小泡的数量,抑制胆碱能神经功能亢进作用,从而改善大鼠的脾虚证候.
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