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Near infrared spectrum for determination of concentration of gliclazide in plasma
Author(s): 
Pages: 722-724
Year: Issue:  12
Journal: Qilu Pharmaceutical Affairs

Abstract: 目的 建立一种高效无损检测格列齐特血药浓度的方法.方法 采用近红外光谱法检测,近红外光谱的检测范围为12500~4000cm-1,分辨率4cm-1,扫描次数为64次.结果 偏最小二乘回归在6200~5400cm-1 范围内进行分析,检测浓度范围在 0.05~2.15μg·mL-1,RMSECV 和RMSEP分别为0.153 和0.467.结论 用近红外光谱对格列齐特血药浓度的测定是可行的.
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