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Effect of dexmedetomidine on the EC50 of propofol target-controlled infusion for respiratory depression
Author(s): 
Pages: 933-935
Year: Issue:  11
Journal: The Journal of Clinical Anesthesiology

Keyword:  右旋美托咪啶丙泊酚呼吸抑制剂量效应关系;
Abstract: 目的 研究右旋美托咪啶对丙泊酚靶控输注(TCI)时患者呼吸抑制的半数有效浓度(EC50)的影响.方法 ASA Ⅰ或Ⅱ级择期全麻手术患者49例,随机分为右旋美托咪啶组(D组)25例和对照组(C组)24例,分别静脉注射右旋美托咪啶0.4 μg/kg或生理盐水5 ml,10 min后开启丙泊酚TCI泵.分别于麻醉前(T1)、输注右旋美托咪啶或生理盐水后1 min(T2)、5 min(T3)和10min(...
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