Research of nuclear factor-κB siRNA to prevent proliferation and restenosis of vein grafts
Author(s): MENG Xiang-bin, BI Yan-wen, FENG Jin-bo, ZHANG Jian-ping, YUE Wei-ming, SONG Guang-min, SUN Wen-yu
Pages: 74-80
Year: 2010 Issue: 11
Journal: Journal of Shandong University(Health Sciences)
Keyword: 静脉移植; 核因子κB; 小干扰RNA; 再狭窄; 模型; 动物; 大鼠; Wistar;
Abstract: 目的 探讨核因子κB(NF-κB)的小干扰RNA(small interfering RNA,siRNA)对大鼠自体静脉移植术后血管内膜增殖及相应炎性细胞因子表达的影响.方珐雄性Wistar大鼠80只,随机分为空白组(A组,n=10);自体静脉移植组(B组,n=18);空载体组(阴性质粒脂质体医用蛋白胶复合物转染移植静脉,C组,n=26)和基因转染组(NF-κB siRNA阳离子脂质体医用蛋白胶复...
Pages: 74-80
Year: 2010 Issue: 11
Journal: Journal of Shandong University(Health Sciences)
Keyword: 静脉移植; 核因子κB; 小干扰RNA; 再狭窄; 模型; 动物; 大鼠; Wistar;
Abstract: 目的 探讨核因子κB(NF-κB)的小干扰RNA(small interfering RNA,siRNA)对大鼠自体静脉移植术后血管内膜增殖及相应炎性细胞因子表达的影响.方珐雄性Wistar大鼠80只,随机分为空白组(A组,n=10);自体静脉移植组(B组,n=18);空载体组(阴性质粒脂质体医用蛋白胶复合物转染移植静脉,C组,n=26)和基因转染组(NF-κB siRNA阳离子脂质体医用蛋白胶复...
Citations
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