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Bronchodilation induced by penehyclidine hydrochloride in chronic obstructive pulmonary disease patients undergoing mechanical ventilation
Author(s): 
Pages: 665-668
Year: Issue:  11
Journal: World Clinical Drugs

Keyword:  盐酸戊乙奎醚慢性阻塞性肺疾病机械通气支气管扩张;
Abstract: 目的 观察盐酸戊乙奎醚对采用机械通气的慢性阻塞性肺疾病(COPD)患者的支气管扩张作用.方法 选择10例应用机械通气的COPD急性加重期患者,雾化吸入盐酸戊乙奎醚1 mg,记录患者给药前后呼吸力学参数、血气分析及心率,并对给药前后的各组数据进行比较.结果 患者的气道峰压、吸气阻力和内源性呼气末正压在给药后15 min即明显下降、肺顺应性明显增加;至3 h时,变化最显著;至12 h时,差异仍有统计学...
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